Anticorps Recombinant de lapin anti-IL-23R

IL-23R Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240905B5

N° de cat : 98180-1-RR

Synonymes

IL23R, interleukin 23 receptor, IL-23 receptor, IL 23R, IL 23 receptor

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98180-1-RR

  1x10^6 HEK-293T cells or IL-23R-transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human IL-23R Rabbit Recombinant Antibody (98180-1-RR, Clone: 240905B5) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed.

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  FC experiment of Transfected HEK-293T using 98180-1-RR

  1x10^6 HEK-293T cells (left) or IL-23R-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Human IL-23R Rabbit Recombinant Antibody (98180-1-RR, Clone: 240905B5) (red) or Isotype Control (blue), and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98180-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98180-1-RR against Human IL-23R were performed. The affinity constant is 2.83 nM.

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Applications testées

• Résultats positifs en cytométrie: Transfected HEK-293T cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98180-1-RR cible IL-23R dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interleukin 23 receptor
• Masse moléculaire calculée: 72 kDa
• Numéro d’acquisition GenBank: NM_144701.3
• Symbole du gène: IL-23R
• Identification du gène (NCBI): 149233
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Interleukin-23 receptor (IL-23R) is a type I cytokine receptor that plays a critical role in immune responses and inflammation. It forms a receptor complex with IL-12Rβ1 and is activated by the cytokine IL-23, which is primarily produced by dendritic cells and activated macrophages (PMID: 39796684). The genetic and epigenetic interactions in the IL-23R/IL-17 axis are associated with elevated expression of IL-17 and inflammatory bowel disease (IBD) pathogenesis (PMID: 21672939).

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