Anticorps Polyclonal de lapin anti-IL-27RA

IL-27RA Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12308-1-PBS

Synonymes

IL27RA, IL 27R alpha, IL 27 receptor subunit alpha, Cytokine receptor-like 1, Cytokine receptor WSX-1

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Galerie de données de validation

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  WB analysis using 12308-1-AP (same clone as 12308-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12308-1-AP (IL-27RA antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12308-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12308-1-PBS cible IL-27RA dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IL-27RA Protéine recombinante Ag2956
• Nom complet: interleukin 27 receptor, alpha
• Masse moléculaire calculée: 636 aa, 69 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC028003
• Symbole du gène: IL27RA
• Identification du gène (NCBI): 9466
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IL-27RA, also known as T-cell cytokine receptor WSX-1 or TCCR, is a unique receptor subunit for the cytokine IL-27. It is expressed in a variety of cells including activated T cells, NK cells, mast cells, endothelial cells, activated B cells, monocytes, Langerhans cells, and activated dendritic cells (PMID: 18378322). The interaction with IL-27 leads to the phosphorylation of Jak and STAT proteins, which are crucial for the regulation of immune responses (PMID: 28536468). IL-27RA plays a significant role in immune cell activation and differentiation, particularly in the context of Th1 and Th17 cells (PMID: 38566992).

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