Anticorps Recombinant de lapin anti-IL-29

IL-29 Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

250226G7

N° de cat : 98504-1-PBS

Synonymes

IL29, Cytokine Zcyto21, IFN lambda 1, IFNL1, IFN-lambda-1

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Galerie de données de validation

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  FC experiment of Transfected CHO using 98504-1-RR (same clone as 98504-1-PBS)

  1x10^6 CHO cells or IL-29 transfected CHO cells were intracellularly stained with0.25 ug Anti-Human IL-29 Rabbit RecAb (98504-1-RR, Clone: 250226G7) and PE-conjugated Goat Anti-Rabbit IgG. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98504-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected CHO using 98504-1-RR (same clone as 98504-1-PBS)

  1x10^6 CHO cells or IL-29 transfected CHO cells were intracellularly stained with 0.25 ug Anti-Human IL-29 Rabbit RecAb (98504-1-RR, Clone: 250226G7) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98504-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98504-1-PBS cible IL-29 dans les applications de FC (Intra) et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-29 Protéine recombinante Eg2843
• Nom complet: interleukin 29 (interferon, lambda 1)
• Masse moléculaire calculée: 22 kDa
• Numéro d’acquisition GenBank: NM_172140.1
• Symbole du gène: IL-29
• Identification du gène (NCBI): 282618
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Interleukin-29 (IL-29) is a cytokine belonging to the Type III interferon family, which has another two subfamilies IL-28A and IL-28B. They are also known as IFN-λ1, IFN-λ2 and IFN-λ3, respectively. IL-29 is produced predominantly by maturing dendritic cells and macrophages. IL-29 plays an important role in the immune response against pathogenes and especially against viruses by mechanisms similar to type I interferons. IL-29 receptor signals through JAK-STAT pathways leading to activated expression of interferon-stimulated genes and production of antiviral proteins.

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