Anticorps Polyclonal de lapin anti-IL-31

IL-31 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22859-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human tonsillitis using 22859-1-AP (same clone as 22859-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22859-1-AP (IL31 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22859-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 22859-1-AP (same clone as 22859-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22859-1-AP (IL31 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22859-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 22859-1-AP (same clone as 22859-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22859-1-AP (IL31 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22859-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 22859-1-AP (same clone as 22859-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22859-1-AP (IL31 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22859-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human small intestine using 22859-1-AP (same clone as 22859-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 22859-1-AP (IL31 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22859-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human small intestine using 22859-1-AP (same clone as 22859-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 22859-1-AP (IL31 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22859-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22859-1-PBS cible IL-31 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: IL-31 Protéine recombinante Ag18848
• Nom complet: interleukin 31
• Masse moléculaire calculée: 164 aa, 18 kDa
• Numéro d’acquisition GenBank: BC132998
• Symbole du gène: IL-31
• Identification du gène (NCBI): 386653
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IL-31 mRNA encodes a 164-aa precursor and a predicted 141-aa mature polypeptide, displaying an apparent molecular mass of 24 kDa in its glycosylated form. IL31 is a newly discovered four-helix bundle cytokine and expressed by several types of cells under both normal and disease state, such as activated CD4+T cells, mast cells, monocytes, macrophages, immature and mature monocyte-derived dendritic cells and so on. IL-31 signals through a heterodimeric receptor complex consisting of the IL31 receptor alpha (IL31Rα) and the oncostatin M receptor (OSMR). IL-31 plays a predominant function in the mediation of inflammatory and lymphoma-associated itch. Increased IL-31 expression has been detected in inflamed tissues from patients with atopic dermatitis, bowel diseases, allergic asthma and rhinitis.

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