Anticorps Recombinant de lapin anti-IL-3RB/CD131

IL-3RB/CD131 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

241954C1

N° de cat : FITC-98232

Synonymes

241954C1, Aic2b, CD131, Csf2rb, Csf2rb1

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using FITC-98232

  1x10^6 mouse bone marrow cells were surface stained with APC Anti-Mouse CD11b, and 0.25 ug FITC Plus Anti-Mouse IL-3RB/CD131 Rabbit RecAb (FITC-98232, Clone: 241954C1) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9). Cells were not fixed.

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  FC experiment of mouse bone marrow cells using FITC-98232

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug FITC Plus Anti-Mouse IL-3RB/CD131 Rabbit RecAb (FITC-98232, Clone:241954C1)(red) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules médullaires de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-98232 cible IL-3RB/CD131 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
• Masse moléculaire calculée: 99kDa
• Numéro d’acquisition GenBank: NM_007780.4
• Symbole du gène: IL-3RB/CD131
• Identification du gène (NCBI): 12983
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD131, also known as IL-3RB, IL-5RB, colony stimulating factor 2 receptor subunit beta (CSF2RB), or cytokine receptor common subunit beta, is the common subunit of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-3 and IL-5 (PMID: 36532080). It is expressed predominantly by hematopoietic cells but also by non-hematopoietic cells (PMID: 10582335). CD131 mediates intracellular signaling by JAK2, leading to phosphorylation of CD131 and triggering signaling pathways such as STAT5, MAPK and PI3-Kinase/AKT which regulate cell survival, proliferation and function (PMID: 23535386).

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