Anticorps Recombinant de lapin anti-IL-4

IL-4 Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

241249H7

N° de cat : 98255-1-PBS

Synonymes

241249H7, B-cell growth factor 1, B-cell IGG differentiation factor, B-cell stimulatory factor 1, BSF-1

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98255-1-RR (same clone as 98255-1-PBS)

  1x10^6 HEK-293T cells or IL-4 transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat IL-4 Rabbit Recombinant Antibody (98255-1-RR, Clone:241249H7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98255-1-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98255-1-RR (same clone as 98255-1-PBS)

  1x10^6 HEK-293T cells (left) or IL-4 transfected HEK-293T cells (right) were intracellularly stained with 0.25 ug Anti-Rat IL-4 Rabbit Recombinant Antibody (98255-1-RR, Clone:241249H7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98255-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98255-1-PBS cible IL-4 dans les applications de FC (Intra) et montre une réactivité avec des échantillons rat

• Réactivité: rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-4 Protéine recombinante Eg1113
• Nom complet: interleukin 4
• Masse moléculaire calculée: 16kDa
• Numéro d’acquisition GenBank: NM_201270.1
• Symbole du gène: IL-4
• Identification du gène (NCBI): 287287
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

IL-4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.

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