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Anticorps Recombinant de lapin anti-IL-5RA/CD125

IL-5RA/CD125 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242234H8

N° de cat : 84948-5-PBS

Synonymes

IL5RA, IL 5R subunit alpha, IL 5R alpha, IL 5 receptor subunit alpha, HSIL5R3

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of human peripheral blood platelets using IL-5RA/CD125 Recombinant antibody (84948-5-RR)

    WB analysis of human peripheral blood platelets using 84948-5-RR (same clone as 84948-5-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 84948-5-RR (IL-5 R alpha/CD125 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84948-5-PBS in a different storage buffer formulation.

Informations sur le produit

84948-5-PBS cible IL-5RA/CD125 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Protéine recombinante
Nom complet interleukin 5 receptor, alpha
Masse moléculaire calculée48 kDa
Poids moléculaire observé60 kDa
Numéro d’acquisition GenBankNM_175726.4
Symbole du gène IL-5RA/CD125
Identification du gène (NCBI) 3568
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Interleukin-5 receptor subunit alpha (IL-5RA), also known as CD125, is a type I transmembrane protein that belongs to the type I cytokine receptor family. IL-5RA is a critical component of the high-affinity IL-5 receptor complex, IL-5R, which consists of the alpha chain (IL-5RA) that specifically binds to IL-5 and the common beta chain (CD131) shared with receptors for IL-3 and GM-CSF (PMID: 1833065; 7872157). IL-5/IL-5RA signaling axis is crucial for the differentiation, proliferation, recruitment, and activation of eosinophils, and is also involved in pathological eosinophilia (PMID: 34638583).

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