Anticorps Monoclonal anti-IL-7
IL-7 Monoclonal Antibody for Cytometric bead array, Indirect ELISA
Hôte / Isotype
Mouse / IgG2b
Réactivité testée
Humain
Applications
Cytometric bead array, Indirect ELISA
Conjugaison
Non conjugué
CloneNo.
5D5G7
N° de cat : 60206-1-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
60206-1-PBS cible IL-7 dans les applications de Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Mouse / IgG2b |
| Clonalité | Monoclonal |
| Type | Anticorps |
| Immunogène | IL-7 Protéine recombinante Ag16314 |
| Nom complet | interleukin 7 |
| Masse moléculaire calculée | 20 kDa |
| Numéro d’acquisition GenBank | BC047698 |
| Symbole du gène | IL-7 |
| Identification du gène (NCBI) | 3574 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par protéine A |
| Tampon de stockage | PBS only |
| Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
IL-7 is one of the members of IL-2 superfamily. IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells, but is not produced by normal lymphocytes. IL7 plays an active role in the development, survival, maintaining and restoring homeostasis of mature T lymphocytes. It is also a key regulator of the commitment, survival, proliferation and maturation of B cells during development. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can be a potent inducer of proinflammatory cytokines and chemokines which may defend against the infection, but may also mediate destructive lung injury. Elevated serum IL7 levels, together with several other circulating cytokines and chemokines, has been found to be associated with the severity of Coronavirus Disease 19 (COVID-19).
