Anticorps Recombinant de lapin anti-IL-7Ra/CD127

IL-7Ra/CD127 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242852B4

N° de cat : 98385-1-PBS

Synonymes

CD127, Il7r, IL 7Ralpha, IL- 7Ralpha, IL-7 receptor subunit alpha

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98385-1-RR (same clone as 98385-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse IL-7Ra/CD127 Rabbit RecAb (98385-1-RR, Clone:242852B4) and PE-Conjugated Goat Anti-Rabbit IgG(H+L), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9). Cells were then stained with APC Anti-Mouse CD3 (17A2) (APC-65077, Clone: 17A2). Cells were not fixed. This data was developed using the same antibody clone with 98385-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98385-1-RR (same clone as 98385-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse IL-7Ra/CD127 Rabbit RecAb (98385-1-RR, Clone:242852B4) (red) and PE-Conjugated Goat Anti-Rabbit IgG(H+L), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98385-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98385-1-RR (same clone as 98385-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse IL-7Ra/CD127 Rabbit RecAb (98385-1-RR, Clone:242852B4) and PE-Conjugated Goat Anti-Rabbit IgG(H+L), or 0.25 ug PE Anti-Mouse IL-7Ra/CD127 (A7R34) (PE-65093, Clone: A7R34). Cells were then stained with APC Anti-Mouse CD3 (17A2) (APC-65077, Clone: 17A2). Cells were not fixed. This data was developed using the same antibody clone with 98385-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98385-1-PBS cible IL-7Ra/CD127 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-7Ra/CD127 Protéine recombinante Eg1826
• Nom complet: interleukin 7 receptor
• Masse moléculaire calculée: 52 kDa
• Numéro d’acquisition GenBank: NM_008372.4
• Symbole du gène: CD127
• Identification du gène (NCBI): 16197
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD127, also known as IL-7R subunit alpha (IL-7Rα), is a type I membrane glycoprotein expressed on thymocytes, B cell precursors, most T cells, and some lymphoid and myeloid cells (PMID: 8415665). IL-7R is a heterodimer composed of CD127 and IL-2Rγ (CD132), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15 (PMID: 8266077; 9862091). IL-7R plays critical roles in lymphocyte development and homeostasis (PMID: 26336149). CD127 can also act as a receptor for thymic stromal lymphopoietin (TSLP) (PMID: 10974032).

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