Anticorps Recombinant de lapin anti-IL-13RA2

IL-13RA2 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA, Sample test

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA, Sample test

Conjugaison

Non conjugué

CloneNo.

250952D10

N° de cat : 86298-2-PBS

Synonymes

IL13RA2, CD213A2, CT19, IL 13 receptor subunit alpha 2, IL 13R

---

Galerie de données de validation

• 

  WB analysis of A375 using 86298-2-RR (same clone as 86298-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86298-2-RR (IL-13RA2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86298-2-PBS in a different storage buffer formulation.

• 

  Sample test of MP02369-1

  The mean IL-13RA2 concentration was determined to be 75.2 ng/mL in A375 cell extract based on a 1.6 mg/mL extract load.

• 

  Cytometric bead array standard curve of MP02369-1

  Cytometric bead array standard curve of MP02369-1, IL-13RA2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 86298-2-PBS. Detection antibody: 86298-1-PBS. Standard: Eg2579. Range: 0.781-100 ng/mL.

---

Informations sur le produit

86298-2-PBS cible IL-13RA2 dans les applications de WB, Cytometric bead array, Indirect ELISA, Sample test et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-13RA2 Protéine recombinante Eg2579
• Nom complet: interleukin 13 receptor, alpha 2
• Masse moléculaire calculée: 380 aa, 44 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC020739
• Symbole du gène: IL13RA2
• Identification du gène (NCBI): 3598
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IL-13RA2, also named as IL-13R and CD213a2, belongs to the type I cytokine receptor family. It binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). IL-13RA2 lacks the cytoplasmic domain for signaling, indicating that it acts as a decoy receptor. IL-13RA2 gene polymorphisms have been associated with systemic sclerosis (PMID: 16981293). Overexpression of IL-13RA2 gene has been reported in several types of cancer, including melanoma, lung cancer, and brain tumor, which makes it a potential immunotherapeutic target (PMID: 19895199; 24970476; 24021875).

{{ptg:RelatedPrimaryAntibodies}}