Anticorps Monoclonal anti-IL-16

IL-16 Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

1C4C7

N° de cat : 66145-1-Ig

Synonymes

IL16, 1C4C7, IL 16, interleukin-16, prIL 16

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Galerie de données de validation

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  WB analysis of Recombinant protein using 66145-1-Ig

  Recombinant protein were subjected to SDS PAGE followed by western blot with 66145-1-Ig (IL-16 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 66145-1-Ig

  Biolayer interferometry (BLl) kinetic assay of 66145-1-Ig against Human IL-16 was performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en WB: Protéine recombinante

Dilution recommandée

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

66145-1-Ig cible IL-16 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: IL-16 Protéine recombinante Ag16466
• Nom complet: interleukin 16 (lymphocyte chemoattractant factor)
• Masse moléculaire calculée: 130 aa, 15 kDa
• Poids moléculaire observé: 37 kDa
• Numéro d’acquisition GenBank: BC040272
• Symbole du gène: IL-16
• Identification du gène (NCBI): 3603
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. It is mainly produced by T lymphocytes but also by other immune cells, neuronal cells, fibroblasts and epithelial cells. The signaling process of this cytokine is mediated by CD4. IL-16 induces chemotaxis of CD4+ cells such as lymphocytes, eosinophils, and dendritic cells by ligating CD4 directly at a site distinct from other ligands. Among its multiple functions, IL-16 is a T cell chemoattractant involved in T helper cell inflammatory responses and the regulation of both T cell growth, and responsiveness to regulatory cytokines. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control.

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