Anticorps Recombinant de lapin anti-IL-17RA

IL-17RA Recombinant Antibody for WB, Sandwich ELISA, Indirect ELISA, Sample test

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Sandwich ELISA, Indirect ELISA, Sample test

Conjugaison

Non conjugué

CloneNo.

241891E11

N° de cat : 84535-2-PBS

Synonymes

CD217, IL17RA, 241891E11, CANDF5, CDw217

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Galerie de données de validation

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  WB analysis using 84535-2-RR (same clone as 84535-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84535-2-RR (IL17RA antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84535-2-PBS in a different storage buffer formulation.

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  Sandwich ELISA standard curve of MP01397-3

  Sandwich ELISA standard curve of MP01397-3, Human IL17RA Recombinant Matched Antibody Pair - PBS only. 84535-3-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg2317. 84535-2-PBS was HRP conjugated as the detection antibody. Range: 0.156-10 ng/mL

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  Sample test of MP01397-3

  The mean IL17RA concentration was determined to be 8.86 ng/mL in MCF-7 cell extract based on a 1.2 mg/mL extract load.

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  Affinity and Kinetic Characterization of 84535-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84535-2-RR against Human IL17RA were performed. The affinity constant is below 1 pM.

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Informations sur le produit

84535-2-PBS cible IL-17RA dans les applications de WB, Sandwich ELISA, Indirect ELISA, Sample test et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-17RA Protéine recombinante Eg2317
• Nom complet: interleukin 17 receptor A
• Masse moléculaire calculée: 866 aa, 96 kDa
• Poids moléculaire observé: 100-130 kDa
• Numéro d’acquisition GenBank: BC011624
• Symbole du gène: IL17RA
• Identification du gène (NCBI): 23765
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Interleukin-17 receptor A (IL17A) is a major effector cytokine of the innate and adaptive immune system and is involved in antimicrobial host defense and maintenance of tissue integrity. It has been shown that IL-17A is involved in the pathogenesis of asthma and allergy and regulates local immune and inflammatory processes in bone tissue and is involved in the onset and progression of osteoporosis. In addition to this, due to polymorphisms in the IL17RA gene, it leads to the development of Fanconi anemia.

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