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Anticorps Recombinant de lapin anti-IL-4

IL-4 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240794A8

N° de cat : 83894-1-PBS

Synonymes

IL4, 240794A8, B-cell stimulatory factor 1, BSF-1, IL 4

Galerie de données de validation

Filter:
  • Immunofluorescence (IF) / fluorescent staining of Raji cells using IL-4 Recombinant antibody (83894-1-RR)

    IF Staining of Raji using 83894-1-RR (same clone as 83894-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Raji cells using IL-4 antibody (83894-1-RR, Clone: 240794A8 ) at dilution of 1:400 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 83894-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83894-1-RR

    Affinity and Kinetic Characterization of 83894-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83894-1-RR against Human IL-4 were performed. The affinity constant is 1.41 nM.

Informations sur le produit

83894-1-PBS cible IL-4 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène IL-4 Protéine recombinante Eg0104
Nom complet interleukin 4
Masse moléculaire calculée 153 aa, 17 kDa
Numéro d’acquisition GenBankBC070123
Symbole du gène IL-4
Identification du gène (NCBI) 3565
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.

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