Anticorps Recombinant de lapin anti-ILT-3/LILRB4

ILT-3/LILRB4 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250356B3

N° de cat : 98486-3-PBS

Synonymes

LILRB4, B4, CD85 antigen-like family member K, CD85k, ILT3

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Galerie de données de validation

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  FC experiment of human PBMCs using 98486-3-RR (same clone as 98486-3-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ILT-3/LILRB4 Rabbit RecAb (98486-3-RR, Clone: 250356B3) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98486-3-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98486-3-RR (same clone as 98486-3-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ILT-3/LILRB4 Rabbit RecAb (98486-3-RR, Clone: 250356B3) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98486-3-PBS in a different storage buffer formulation.

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Informations sur le produit

98486-3-PBS cible ILT-3/LILRB4 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ILT-3/LILRB4 Protéine recombinante Eg1743
• Nom complet: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
• Masse moléculaire calculée: 49kDa
• Numéro d’acquisition GenBank: AAH26309.1
• Symbole du gène: LILRB4
• Identification du gène (NCBI): 11006
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

LILRB4 is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid origin. LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory motifs to initiate different signaling cascades, thus playing an important role in physiological and pathological conditions, including autoimmune diseases, microbial infections, and cancers.

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