Anticorps Monoclonal anti-INPP5E

INPP5E Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2B3D6

N° de cat : 68602-1-PBS

Synonymes

INPP5E, PPI5PIV

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Galerie de données de validation

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  WB analysis using 68602-1-Ig (same clone as 68602-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68602-1-Ig (INPP5E antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68602-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68602-1-Ig (same clone as 68602-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68602-1-Ig (INPP5E antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68602-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HaCaT using 68602-1-Ig (same clone as 68602-1-PBS)

  HaCaT cells were subjected to SDS PAGE followed by western blot with 68602-1-Ig (INPP5E antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68602-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68602-1-PBS cible INPP5E dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: INPP5E Protéine recombinante Ag11959
• Nom complet: inositol polyphosphate-5-phosphatase, 72 kDa
• Masse moléculaire calculée: 644 aa, 70 kDa
• Poids moléculaire observé: 72 kDa
• Numéro d’acquisition GenBank: BC028032
• Symbole du gène: INPP5E
• Identification du gène (NCBI): 56623
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

INPP5E(72 kDa inositol polyphosphate 5-phosphatase) converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2.In mouse, highest protein expression was in brain, heart, and testis, with lower expression in thymus and lung, and very little expression in kidney, spleen, and liver(PMID:10764818). Defects in INPP5E are the cause of Joubert syndrome type 1 (JBTS1) and mental retardation-truncal obesity-retinal dystrophy-micropenis (MORMS)(PMID:19668215).

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