Anticorps Recombinant de lapin anti-INSR/CD220

INSR/CD220 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

241687A10

N° de cat : CL647-98227

Synonymes

INSR, 241687A10, CD220, EC:2.7.10.1, HHF5

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Galerie de données de validation

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  FC experiment of human PBMCs using CL647-98227

  1x10^6 human PBMCs were surface stained with CoraLite® Plus 488 Anti-Human CD14 Rabbit Recombinant Antibody (CL488-98040, Clone: 230332D7), and 5 ul CoraLite® Plus 647 Anti-Human INSR/CD220 Rabbit RecAb (CL647-98227, Clone:241687A10) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using CL647-98227

  1x10^6 human PBMCs were surface stained with 5 ul CoraLite® Plus 647 Anti-Human INSR/CD220 Rabbit RecAb (CL647-98227, Clone:241687A10)(red) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98227 cible INSR/CD220 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: INSR
• Numéro d’acquisition GenBank: BC117172
• Symbole du gène: INSR
• Identification du gène (NCBI): 3643
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

The biological effects of INS are mediated by a membrane-spanning cell surface receptor that has been shown to consist of disulfide-linked alpha-subunits (135 kDa) and beta-subunits (95 kDa) that are cleaved products of a common precursor. The binding of INS to the receptor extracellular domain results in intracellular activation of a tyrosine-specific kinase activity and the generation of signals that determine the cellular response (PMID: 2369896).

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