Anticorps Polyclonal de lapin anti-INSRR

INSRR Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55112-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse kidney using 55112-1-AP (same clone as 55112-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55112-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 55112-1-AP (same clone as 55112-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55112-1-PBS in a different storage buffer formulation.

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Informations sur le produit

55112-1-PBS cible INSRR dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: IR related receptor
• Masse moléculaire calculée: 144 kDa
• Poids moléculaire observé: 150-155 kDa
• Numéro d’acquisition GenBank: NM_014215
• Symbole du gène: INSRR
• Identification du gène (NCBI): 3645
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

INSRR, also named as IRR, belongs to the protein kinase superfamily, Tyr protein kinase family and INS receptor subfamily. It probably binds an INS related protein and has a tyrosine-protein kinase activity. It phosphorylates the INS receptor substrates IRS-1 and IRS-2. INSRR is a heterotetrameric transmembrane receptor composed of two alpha and two beta chains linked by disulfide bonds. INSRR shares high homology with the INS (IR) and the IGF-1R, but doesn't bind any of IR and IGF-1R known ligands. The antibody is specific to INSRR.

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