Anticorps Polyclonal de lapin anti-INTS8

INTS8 Polyclonal Antibody for WB, IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18802-1-PBS

Synonymes

Protein kaonashi-1, Protein kaonashi 1, Integrator complex subunit 8, Int8, C8orf52

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Galerie de données de validation

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  WB analysis of MCF-7 using 18802-1-AP (same clone as 18802-1-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 18802-1-AP (INTS8 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18802-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 18802-1-AP (same clone as 18802-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 18802-1-AP (INTS8 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18802-1-PBS in a different storage buffer formulation.

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  IP experiment of HeLa using 18802-1-AP (same clone as 18802-1-PBS)

  IP result of anti-INTS8 (IP:18802-1-AP, 4ug; Detection:18802-1-AP 1:500) with HeLa cells lysate 4000ug. This data was developed using the same antibody clone with 18802-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 18802-1-AP (same clone as 18802-1-PBS)

  Immunofluorescent analysis of Hela cells, using INTS8 antibody 18802-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). This data was developed using the same antibody clone with 18802-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18802-1-PBS cible INTS8 dans les applications de WB, IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: integrator complex subunit 8
• Masse moléculaire calculée: 111 kDa
• Poids moléculaire observé: 95-111 kDa
• Numéro d’acquisition GenBank: BC136754
• Symbole du gène: INTS8
• Identification du gène (NCBI): 55656
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Integrator complex subunit 8 (INTS8) is one of the major components of RNA polymerase II and has been demonstrated to be involved in the cleavage of small nuclear RNAs and transcriptional processes (PMID: 34880328). INTS8 was robustly increased in neurodevelopmental diseases and numerous tumors. High INTS8 expression has a tight correlation with poor prognosis in multi-cancers (PMID: 30881114). Western blot analysis detected INTS8 at an apparent molecular mass of 111 kDa.

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