Anticorps Monoclonal anti-IQGAP1

IQGAP1 Monoclonal Antibody for WB, IHC, ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, rat

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

2E11A2

N° de cat : 68588-1-PBS

Synonymes

2E11A2, HUMORFA01, KIAA0051, p195, Ras GTPase-activating-like protein IQGAP1

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Galerie de données de validation

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  WB analysis using 68588-1-Ig (same clone as 68588-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68588-1-Ig (IQGAP1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68588-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin cancer using 68588-1-Ig (same clone as 68588-1-PBS)

  Immunohistochemical analysis of paraffin-embedded skin cancer slide using 68588-1-Ig (IQGAP1 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68588-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68588-1-PBS cible IQGAP1 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: IQGAP1 Protéine recombinante Ag19321
• Nom complet: IQ motif containing GTPase activating protein 1
• Masse moléculaire calculée: 189 kDa
• Poids moléculaire observé: 190-195 kDa
• Numéro d’acquisition GenBank: BC151834
• Symbole du gène: IQGAP1
• Identification du gène (NCBI): 8826
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IQGAP1 is a member of a family of scaffolding proteins that interact with signaling and structural molecules. It localizes to sites of cell-cell contact in epithelial cells and regulates distinct cellular processes including cell adhesion, cell migration, extracellular signals through interacting with numerous protein. Multiple studies have shown that IQGAP1 is up-regulated in many human malignancies, such as lung cancer, ovarian cancer, colon cancer, breast cancer, melanoma and HCC. And IQGAP1 plays a critical role in cancer cell invasion.

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