Anticorps Recombinant de lapin anti-IQUB

IQUB Recombinant Antibody for IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

240957A11

N° de cat : 83847-5-PBS

Synonymes

IQ motif and ubiquitin-like domain-containing protein, 240957A11

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Galerie de données de validation

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  IHC staining of mouse testis using 83847-5-RR (same clone as 83847-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 83847-5-RR (IQUB antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83847-5-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 83847-5-RR (same clone as 83847-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 83847-5-RR (IQUB antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83847-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83847-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83847-5-RR against Human IQUB were performed. The affinity constant is 0.144 nM.

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Informations sur le produit

83847-5-PBS cible IQUB dans les applications de IHC, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IQUB Protéine recombinante Ag19507
• Nom complet: IQ motif and ubiquitin domain containing
• Masse moléculaire calculée: 791 aa, 93 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC128181
• Symbole du gène: IQUB
• Identification du gène (NCBI): 154865
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IQUB (IQ motif and ubiquitin domain containing) was discovered in 2002,4 which was located on chromosome 7q31.32 and its encoded protein mainly contained 2 domains, ubiquitin-like domain and IQ domain. IQUB had apparently higher expression in breast cancer than that in normal tissues, suggesting that it may act an important role in the occurrence and development of breast cancer (PMID: 29968965). IQUB is a critical RS1 adaptor in mouse sperm flagella, and is critical for sperm motility and fertilization (PMID: 36417862).

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