Anticorps Monoclonal anti-IRF5

IRF5 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3A4A10

N° de cat : 66835-1-PBS

Synonymes

3A4A10, interferon regulatory factor 5, IRF 5, IRF-5 , SLEB10

---

Galerie de données de validation

• 

  WB analysis of A549 using 66835-1-Ig (same clone as 66835-1-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

• 

  WB analysis of THP-1 using 66835-1-Ig (same clone as 66835-1-PBS)

  THP-1 cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

• 

  WB analysis of RAW 264.7 using 66835-1-Ig (same clone as 66835-1-PBS)

  RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 66835-1-Ig (same clone as 66835-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

66835-1-PBS cible IRF5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: IRF5 Protéine recombinante Ag5442
• Nom complet: interferon regulatory factor 5
• Masse moléculaire calculée: 56 kDa
• Poids moléculaire observé: 56 kDa
• Numéro d’acquisition GenBank: BC004201
• Symbole du gène: IRF5
• Identification du gène (NCBI): 3663
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. It is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10). IRF5 is also used as M1 marcrophage lineage marker. Alternative splice variant encoding different isoforms exist.

{{ptg:RelatedPrimaryAntibodies}}