Anticorps Recombinant de lapin anti-ISLR

ISLR Recombinant Antibody for WB, IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

240727D4

N° de cat : 83782-5-PBS

Synonymes

240727D4, HsT17563, Immunoglobulin superfamily containing leucine-rich repeat protein, UNQ189/PRO215

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Galerie de données de validation

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  WB analysis using 83782-5-RR (same clone as 83782-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83782-5-RR (ISLR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83782-5-PBS in a different storage buffer formulation.

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  WB analysis of mouse retina using 83782-5-RR (same clone as 83782-5-PBS)

  mouse retina tissue were subjected to SDS PAGE followed by western blot with 83782-5-RR (ISLR antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83782-5-PBS in a different storage buffer formulation.

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  IHC staining of mouse eye using 83782-5-RR (same clone as 83782-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 83782-5-RR (ISLR antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83782-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83782-5-PBS

  Biolayer interferometry (BLl) kinetic assays of 83782-5-PBS against Human ISLR were performed. The affinity constant is 1.30 nM.

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  Affinity and Kinetic Characterization of 83782-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83782-5-RR against Human ISLR were performed. The affinity constant is 0.369 nM.

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Informations sur le produit

83782-5-PBS cible ISLR dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ISLR Protéine recombinante Ag19446
• Nom complet: immunoglobulin superfamily containing leucine-rich repeat
• Masse moléculaire calculée: 428 aa, 46 kDa
• Poids moléculaire observé: 44-46 kDa
• Numéro d’acquisition GenBank: BC022478
• Symbole du gène: ISLR
• Identification du gène (NCBI): 3671
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The Immunoglobulin superfamily containing leucine-rich repeat protein(ISLR), is involved in various biological events, such as embryonic development, Gaucher's disease, and replicative senescence of fibroblasts in some organs, including the heart, pancreas, and bone marrow. ISLR, also known as meflin, is a newly discovered marker of mesenchymal stem cells, which is involved in pathological fibrosis and the cancer microenvironment. (PMID: 34713300)

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