Anticorps Recombinant de lapin anti-ISLR2
ISLR2 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
WB, Cytometric bead array, Indirect ELISA
Conjugaison
Non conjugué
CloneNo.
241227D3
N° de cat : 84076-1-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
84076-1-PBS cible ISLR2 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Recombinant |
| Type | Anticorps |
| Immunogène | ISLR2 Protéine recombinante Ag20505 |
| Nom complet | immunoglobulin superfamily containing leucine-rich repeat 2 |
| Masse moléculaire calculée | 745 aa, 79 kDa |
| Numéro d’acquisition GenBank | BC152429 |
| Symbole du gène | ISLR2 |
| Identification du gène (NCBI) | 57611 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par protéine A |
| Tampon de stockage | PBS only |
| Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2), also known as LINX. It is expected to be located in cell membrane and the protein is mainly expressed in brain and testis. While the first knockout mouse had impaired development of the internal capsule and no hydrocephalus, a much more recent independent knockout mouse was shown to additionally have severe hydrocephalus. Although the mechanism remains unclear, it may be related to the role of ISLR2 in reorganizing the cytoskeleton of developing neurons (PMID: 30483960). The calculated molecular weight of ISLR2 is 79 kDa, this target has phosphorylation modification and glycosylation modification. And the 130 kDa band is glycosylated (PMID: 29739947).
