Anticorps Polyclonal de lapin anti-ITIH1

ITIH1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21141-1-PBS

Synonymes

Inter-alpha-inhibitor heavy chain 1, Inter-alpha-trypsin inhibitor complex component III, Inter-alpha-trypsin inhibitor heavy chain H1, Serum-derived hyaluronan-associated protein

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Galerie de données de validation

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  WB analysis using 21141-1-AP (same clone as 21141-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21141-1-AP (ITIH1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21141-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21141-1-PBS cible ITIH1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ITIH1 Protéine recombinante Ag15598
• Nom complet: inter-alpha (globulin) inhibitor H1
• Masse moléculaire calculée: 911 aa, 101 kDa
• Poids moléculaire observé: 70-76 kDa
• Numéro d’acquisition GenBank: BC069464
• Symbole du gène: ITIH1
• Identification du gène (NCBI): 3697
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ITIH1 (inter-alpha-trypsin inhibitor heavy chain 1), also named as IGHEP1 and SHAP. It is a key component of the inter-alpha-trypsin inhibitor (ITI) family, which plays a crucial role in extracellular matrix (ECM) stabilization and inflammation regulation. ITIH1 forms a complex with bikunin (a light chain) and other heavy chains (ITIH2, ITIH3, ITIH4), contributing to the stabilization of hyaluronan-rich matrices. The calculated molecular weight of the ITIH1 mature form is 101 kDa, but the actual observed molecular weight is about 76 kDa (PMID: 9677337).

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