Anticorps Polyclonal de lapin anti-ITLN1/2

ITLN1/2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11770-1-PBS

Synonymes

ITLN1, HL 1, hIntL, Galactofuranose-binding lectin, Galactofuranose binding lectin

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Galerie de données de validation

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  WB analysis of mouse colon using 11770-1-AP (same clone as 11770-1-PBS)

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 11770-1-AP (ITLN1/2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11770-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse appendix using 11770-1-AP (same clone as 11770-1-PBS)

  IP result of anti-ITLN1/2 (IP:11770-1-AP, 4ug; Detection:11770-1-AP 1:500) with mouse appendix tissue lysate 4000ug. This data was developed using the same antibody clone with 11770-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach using 11770-1-AP (same clone as 11770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 11770-1-AP (ITLN1/2 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11770-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11770-1-PBS cible ITLN1/2 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ITLN1/2 Protéine recombinante Ag2424
• Nom complet: intelectin 1 (galactofuranose binding)
• Masse moléculaire calculée: 313 aa, 35 kDa
• Poids moléculaire observé: 35-40 kDa
• Numéro d’acquisition GenBank: BC020664
• Symbole du gène: ITLN1
• Identification du gène (NCBI): 55600
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ITLN1, also named as Intelectin 1, has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 is a glycoprotein made up of three 40 kDa subunits cross-linked by disulfide bonds making up a 120-kDa homo-trimer of 295 amino acids and N-linked oligosaccharides (PMID: 17621593). It may play a role in the defense system against microorganisms. Human intelectin-1 is expressed in intestinal goblet cells, and is present at about 200 ng/mL in serum. Intelectin-1 was also shown to be expressed in human endothelial cells and adipocytes of human abdominal adipose tissue. (PMID: 22768319,PMID: 28640441)

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