Anticorps Recombinant de lapin anti-ITPR1-Specific

ITPR1-Specific Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242274B10

N° de cat : 85101-1-PBS

Synonymes

ITPR1, 242274B10, ACV, Inositol 1,4,5 trisphosphate receptor, Inositol 1,4,5-trisphosphate receptor type 1

---

Galerie de données de validation

• 

  WB analysis using 85101-1-RR (same clone as 85101-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85101-1-RR (ITPR1-specific antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85101-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 85101-1-RR (same clone as 85101-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85101-1-RR (ITPR1-Specific antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85101-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 85101-1-RR (same clone as 85101-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85101-1-RR (ITPR1-Specific antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85101-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

85101-1-PBS cible ITPR1-Specific dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: inositol 1,4,5-triphosphate receptor, type 1
• Masse moléculaire calculée: 314 kDa
• Poids moléculaire observé: 290-300 kDa
• Numéro d’acquisition GenBank: NM_001099952
• Symbole du gène: ITPR1
• Identification du gène (NCBI): 3708
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ITPR1, also named as INSP3R1 and IP3R, belongs to the InsP3 receptor family. It is a receptor for inositol 1,4,5-trisphosphate which is a second messenger that mediates the release of intracellular calcium. Defects in ITPR1 are the cause of spinocerebellar ataxia type 15 (SCA15). The antibody has no cross reaction with ITPR2 and ITPR3.

{{ptg:RelatedPrimaryAntibodies}}