Anticorps Recombinant de lapin anti-IL-15RA

IL-15RA Recombinant Antibody for FC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242618B9

N° de cat : 98406-2-PBS

Synonymes

CD215, IL-15 receptor subunit alpha, Il15ra, IL-15R-alpha, Interleukin-15 receptor subunit alpha

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98406-2-RR (same clone as 98406-2-PBS)

  1x10^6 HEK-293T cells or IL-15RA transfected HEK-293T cells were surface stained with 0.25 ug Anti-Mouse IL-15RA Rabbit RecAb (98406-2-RR, Clone: 242618B9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98406-2-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98406-2-RR (same clone as 98406-2-PBS)

  1x10^6 HEK-293T cells or IL-15RA-transfected HEK-293T cells were surface stained with 0.25 ug Anti-Mouse IL-15RA Rabbit RecAb (98406-2-RR, Clone: 242618B9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98406-2-PBS in a different storage buffer formulation.

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Informations sur le produit

98406-2-PBS cible IL-15RA dans les applications de FC, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-15RA Protéine recombinante Eg2687
• Nom complet: interleukin 15 receptor, alpha chain
• Masse moléculaire calculée: 28 kDa
• Numéro d’acquisition GenBank: NM_008358.2
• Symbole du gène: Il15ra
• Identification du gène (NCBI): 16169
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Interleukin-15 (IL-15) is a pleiotropic cytokine that plays an important role in both innate and adaptive immunity. IL-15 is mainly produced by activated monocytes, macrophages and dendritic cells, and is structurally similar to IL-2 (PMID: 8178155; 12401478). These two cytokines share the same IL-2/15Rβ and common γ-chain receptor subunits. In addition, IL-2 and IL-15 have their own private α-chain receptor subunit, IL-2Rα and IL-15Rα, respectively (PMID: 7641685). The IL-15Rα chain is expressed by many cell types including monocytes, DCs, NK, T cells and fibroblasts. Several isoforms of IL-15Rα exist and are generated either by alternative splicing or by proteolytic cleavage (PMID: 10480910; 15265897).

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