Anticorps Recombinant de lapin anti-Importin Beta

Importin Beta Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251633D12

N° de cat : 86630-3-PBS

Synonymes

KPNB1, IMB1, Impnb, Importin 90, Importin subunit beta 1

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Galerie de données de validation

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  WB analysis using 86630-3-RR (same clone as 86630-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86630-3-RR (KPNB1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86630-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86630-3-RR

  Biolayer interferometry (BLl) kinetic assays of 86630-3-RR against Human Importin Beta were performed. The affinity constant is 1.02 nM.

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Informations sur le produit

86630-3-PBS cible Importin Beta dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Importin Beta Protéine recombinante Ag0122
• Nom complet: karyopherin (importin) beta 1
• Masse moléculaire calculée: 97 kDa
• Poids moléculaire observé: 90-97 kDa
• Numéro d’acquisition GenBank: BC003572
• Symbole du gène: KPNB1
• Identification du gène (NCBI): 3837
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Importin beta1, also known karyopherin beta or KPNB1, is a nuclear transport receptor that plays a key role in the nuclear import process. Importin beta1 and importin alpha work in concert to transport cargo into the nucleus, functioning as an essential component of the classical nuclear localization signal (NLS) pathway. Elevated expression of importin beta1 has been found in cervical tumors. (22125623)

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