Anticorps Monoclonal anti-Integrin Alpha 4

Integrin Alpha 4 Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

1B6A3

N° de cat : 67040-1-PBS

Synonymes

ITGA4, 1B6A3, CD49 antigen-like family member D, CD49D, IA4

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Galerie de données de validation

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  WB analysis using 67040-1-Ig (same clone as 67040-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67040-1-Ig (Integrin Alpha 4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67040-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 67040-1-Ig (same clone as 67040-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67040-1-Ig (Integrin Alpha 4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67040-1-PBS in a different storage buffer formulation.

• 

  WB analysis of NK-92 using 67040-1-Ig (same clone as 67040-1-PBS)

  NK-92 cells were subjected to SDS PAGE followed by western blot with 67040-1-Ig (Integrin Alpha 4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67040-1-PBS in a different storage buffer formulation.

• 

  WB analysis of U-937 using 67040-1-Ig (same clone as 67040-1-PBS)

  U-937 cells were subjected to SDS PAGE followed by western blot with 67040-1-Ig (Integrin Alpha 4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67040-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67040-1-PBS cible Integrin Alpha 4 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Integrin Alpha 4 Protéine recombinante Ag28024
• Nom complet: integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
• Masse moléculaire calculée: 1032 aa, 115 kDa
• Poids moléculaire observé: 130-150 kDa
• Numéro d’acquisition GenBank: BC156712
• Symbole du gène: Integrin alpha 4
• Identification du gène (NCBI): 3676
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. I It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

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