Anticorps Polyclonal de lapin anti-JAK2

• Phare
• Validé par KD/KO

JAK2 Polyclonal Antibody for WB, IHC, IP, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IP, ELISA

Conjugaison

Non conjugué

N° de cat : 17670-1-PBS

Synonymes

Tyrosine protein kinase JAK2, JTK10, Janus kinase 2, JAK-2, JAK 2

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Galerie de données de validation

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  WB analysis of NIH/3T3 using 17670-1-AP (same clone as 17670-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 17670-1-AP (JAK2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17670-1-PBS in a different storage buffer formulation.

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  IP experiment of NIH/3T3 using 17670-1-AP (same clone as 17670-1-PBS)

  IP result of anti-JAK2 (IP:17670-1-AP, 4ug; Detection:17670-1-AP 1:300) with NIH/3T3 cells lysate 3440 ug. This data was developed using the same antibody clone with 17670-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 17670-1-AP (same clone as 17670-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 17670-1-AP (JAK2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17670-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 17670-1-AP (same clone as 17670-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 17670-1-AP (JAK2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17670-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 17670-1-AP (same clone as 17670-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17670-1-AP (JAK2 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17670-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 17670-1-AP (same clone as 17670-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17670-1-AP (JAK2 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17670-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17670-1-PBS cible JAK2 dans les applications de WB, IHC, IP, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: JAK2 Protéine recombinante Ag11264
• Nom complet: Janus kinase 2 (a protein tyrosine kinase)
• Masse moléculaire calculée: 1132 aa, 130 kDa
• Poids moléculaire observé: 120-130 kDa
• Numéro d’acquisition GenBank: BC039695
• Symbole du gène: JAK2
• Identification du gène (NCBI): 3717
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Janus kinases (JAKs) are non-receptor tyrosine kinases that are activated by cytokine binding to cytokine receptors resulting in stimulation of the JAK-STAT signaling pathway. Aberrant activation of this signaling pathway is associated with numerous immune disorders and cancer.

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