Anticorps Recombinant de lapin anti-JAK3

JAK3 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3N1

N° de cat : 80331-1-PBS

Synonymes

3N1, EC:2.7.10.2, JAK 3, JAK-3, JAKL

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Galerie de données de validation

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  WB analysis using 80331-1-RR (same clone as 80331-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 80331-1-RR (JAK3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 80331-1-RR (same clone as 80331-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 80331-1-RR (JAK3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 80331-1-RR (same clone as 80331-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 80331-1-RR (JAK3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

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Informations sur le produit

80331-1-PBS cible JAK3 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: Janus kinase 3 (a protein tyrosine kinase, leukocyte)
• Masse moléculaire calculée: 1124 aa, 125 kDa
• Poids moléculaire observé: 125 kDa
• Numéro d’acquisition GenBank: BC028068
• Symbole du gène: JAK3
• Identification du gène (NCBI): 3718
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

JAK3 is a non-receptor tyrosine kinase, predominantly expressed in hematopoietic cells and that has been implicated in the signal transduction of the common gamma chain subfamily of cytokine receptors. As a result, JAK3 plays an essential role in hematopoieisis during T cell development. JAK3 belongs to the Janus kinase family of receptor-associated tyrosine kinases located in cytoplasm adjacent to the plasma membrane. (PMID: 19747563, PMID: 33767339)

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