Anticorps Recombinant de lapin anti-JAM-A/CD321

JAM-A/CD321 Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250060H5

N° de cat : 86229-1-PBS

Synonymes

CD321, F11r, Jam1, JAM-1, JAM-A

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Galerie de données de validation

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  WB analysis using 86229-1-RR (same clone as 86229-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86229-1-RR (F11r(CD321) antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86229-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 86229-1-RR (same clone as 86229-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86229-1-RR (F11r(CD321) antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86229-1-PBS in a different storage buffer formulation.

• 

  IF Staining of bEnd.3 using 86229-1-RR (same clone as 86229-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed bEnd.3 cells using JAM-A/CD321 antibody (86229-1-RR, Clone: 250060H5 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 86229-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86229-1-PBS cible JAM-A/CD321 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: JAM-A/CD321 Protéine recombinante Eg3117
• Nom complet: F11 receptor
• Masse moléculaire calculée: 32 kDa
• Poids moléculaire observé: 33 kDa
• Numéro d’acquisition GenBank: NM_172647.2
• Symbole du gène: F11r
• Identification du gène (NCBI): 16456
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Junctional Adhesion Molecule-A (JAM-A), also known as CD321 or F11R, is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is primarily located in the tight junctions of epithelial and endothelial cells and is also expressed on circulating platelets and leukocytes (PMID: 34533648). Targeting F11R/JAM-A with monoclonal antibodies or peptide antagonists has shown promise in inhibiting tumor growth and metastasis in mouse models (PMID: 37563645).

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