Anticorps Recombinant de lapin anti-JAM2/CD322

JAM2/CD322 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242617F10

N° de cat : 98390-1-PBS

Synonymes

JAM2, C21orf43, CD322, JAM-2, JAMB

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98390-1-RR (same clone as 98390-1-PBS)

  1x10^6 HEK-293T cells or JAM2/CD322 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human JAM2/CD322 Rabbit RecAb (98390-1-RR, Clone: 242617F10) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98390-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98390-1-RR (same clone as 98390-1-PBS)

  1x10^6 HEK-293T cells or JAM2/CD322 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human JAM2/CD322 Rabbit RecAb (98390-1-RR, Clone: 242617F10) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98390-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98390-1-PBS cible JAM2/CD322 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: JAM2/CD322 Protéine recombinante Eg2914
• Nom complet: junctional adhesion molecule 2
• Masse moléculaire calculée: 33 kDa
• Numéro d’acquisition GenBank: NM_021219.3
• Symbole du gène: JAM2
• Identification du gène (NCBI): 58494
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Junctional adhesion molecules (JAMs) are integral membrane proteins belonging to the immunoglobulin (Ig) superfamily. JAMs are expressed by leukocytes, platelets, endothelial, and epithelial cells and localized at the tight junction of polarized cells and on the cell surface of leukocytes. JAM-2, also known as CD322, VE-JAM or JAM-B, is specifically expressed in lymphatic endothelial cells and endothelial venules. JAM2 regulates cell-cell adhesion and signaling by interacting with other tight junction proteins such as PAR-3 and ZO-1.

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