Anticorps Recombinant de lapin anti-KATNAL1

KATNAL1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242796B5

N° de cat : 85382-1-PBS

Synonymes

p60 katanin like 1, Katanin p60 subunit A-like 1, katanin p60 subunit A like 1, Katanin p60 ATPase-containing subunit A-like 1, EC:5.6.1.1

---

Galerie de données de validation

• 

  WB analysis using 85382-1-RR (same clone as 85382-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85382-1-RR (KATNAL1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85382-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 85382-1-RR (same clone as 85382-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85382-1-RR (KATNAL1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85382-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

85382-1-PBS cible KATNAL1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: KATNAL1 Protéine recombinante Ag13960
• Nom complet: katanin p60 subunit A-like 1
• Masse moléculaire calculée: 490 aa, 55 kDa
• Poids moléculaire observé: 50-55 kDa
• Numéro d’acquisition GenBank: BC000612
• Symbole du gène: KATNAL1
• Identification du gène (NCBI): 84056
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

KATNAL1 belongs to a family of microtubule-severing proteins and contains an N-terminal microtubule interaction and trafficking (MIT) domain, an ATPase AAA-type core domain, and a C-terminal Vps4_C domain. KATNAL1 is involved in regulating microtubule dynamics, which is essential for spermiogenesis and male fertility. It severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays(PMID: 22654668). In neurons, KATNAL1 plays a role in microtubule rearrangement during neuronal migration and process elongation. Additionally, mutations in KATNAL1 have been associated with intellectual disability and microcephaly in humans(PMID: 30448058).

{{ptg:RelatedPrimaryAntibodies}}