Anticorps Polyclonal de lapin anti-KCNE2

KCNE2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17920-1-PBS

Synonymes

MinK-related peptide 1, MinK related peptide 1, Minimum potassium ion channel-related peptide 1, LQT6, LQT5

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Galerie de données de validation

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  WB analysis using 17920-1-AP (same clone as 17920-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17920-1-AP (KCNE2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17920-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17920-1-PBS cible KCNE2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KCNE2 Protéine recombinante Ag12336
• Nom complet: potassium voltage-gated channel, Isk-related family, member 2
• Masse moléculaire calculée: 123 aa, 14 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC093892
• Symbole du gène: KCNE2
• Identification du gène (NCBI): 9992
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Potassium voltage-gated channel subfamily E regulatory subunit 2 (KCNE2, also known as LQT5, LQT6, ATFB4, and MIRP1) functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits (PMID: 10219239; 11034315; 11101505; 12185453; 20533308). KCNE2 beta subunit modulates the gating kinetics and enhances the stability of the channel complex (PMID: 10219239; 11034315; 11101505; 12185453; 20533308). It is expressed in various parts of the heart, with higher levels observed in the ventricles and Purkinje tissues compared to the atria (PMID: 39272981). KCNE2 has three forms, such as the core (15 kDa), singly glycosylated (20 kDa), and doubly glycosylated (25 kDa) forms (PMID: 15066947).

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