Anticorps Polyclonal de lapin anti-KCNQ5

KCNQ5 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28000-1-PBS

Synonymes

Voltage-gated potassium channel subunit Kv7.5, Potassium voltage-gated channel subfamily KQT member 5, Kv7.5, KQT-like 5, KQT like 5

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Galerie de données de validation

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  WB analysis using 28000-1-AP (same clone as 28000-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28000-1-AP (KCNQ5 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28000-1-PBS in a different storage buffer formulation.

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  IP experiment of Raji using 28000-1-AP (same clone as 28000-1-PBS)

  IP result of anti-KCNQ5 (IP:28000-1-AP, 4ug; Detection:28000-1-AP 1:500) with Raji cells lysate 1600 ug. This data was developed using the same antibody clone with 28000-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28000-1-PBS cible KCNQ5 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KCNQ5 Protéine recombinante Ag27622
• Nom complet: potassium voltage-gated channel, KQT-like subfamily, member 5
• Masse moléculaire calculée: 102 kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: NM_001160130
• Symbole du gène: KCNQ5
• Identification du gène (NCBI): 56479
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Potassium voltage-gated channel subfamily Q member 5 (KCNQ5, also known as Kv7.5 and MRD46) is widely expressed in the brain and generates M-type current. It has a role in the regulation of neuronal excitability (PMID: 10816588). KCNQ5 mutations are associated with increased excitability and decreased repolarization reserve, lead to pathophysiology (PMID: 28669405).

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