Anticorps Recombinant de lapin anti-KCNV1

KCNV1 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

242865E3

N° de cat : 85153-3-RR

Synonymes

242865E3, HNKA, KCNB3, KV2.3, KV8.1

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Galerie de données de validation

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  WB analysis using 85153-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 85153-3-RR (KCNV1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  WB analysis using 85153-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 85153-3-RR (KCNV1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  IHC staining of mouse brain using 85153-3-RR

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85153-3-RR (KCNV1 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of rat brain using 85153-3-RR

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85153-3-RR (KCNV1 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  Affinity and Kinetic Characterization of 85153-3-RR

  Biolayer interferometry (BLl) kinetic assays of 85153-3-RR against Human KCNV1 were performed. The affinity constant is 0.70 nM.

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Applications testées

• Résultats positifs en WB: tissu cérébral de souris, cellules C6, cellules MG U-87, tissu cérébral de rat, tissu cérébral humain fœtal

Dilution recommandée

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

85153-3-RR cible KCNV1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: KCNV1 Protéine recombinante Ag3376
• Nom complet: potassium channel, subfamily V, member 1
• Masse moléculaire calculée: 500 aa, 56 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC028739
• Symbole du gène: KCNV1
• Identification du gène (NCBI): 27012
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Potassium voltage-gated channel subfamily V member 1 (KCNV1, also known as Kv8.1) is a voltage-gated potassium channel that plays a role in the repolarization phase of the action potential (PMID: 39003683). It is involved in regulating neuronal excitability and is essential for maintaining normal electrical signaling in the nervous system (PMID: 38911266). The function of KCNV1 may also include inhibiting specific types of outwardly rectifying potassium channels (PMID: 8670833).

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