Anticorps Polyclonal de lapin anti-KCTD4

KCTD4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32898-1-PBS

Synonymes

BTB/POZ domain-containing protein KCTD4

---

Galerie de données de validation

• 

  WB analysis using 32898-1-AP (same clone as 32898-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32898-1-AP (KCTD4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32898-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

32898-1-PBS cible KCTD4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KCTD4 Protéine recombinante Ag37112
• Nom complet: potassium channel tetramerisation domain containing 4
• Masse moléculaire calculée: 30 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC018063
• Symbole du gène: KCTD4
• Identification du gène (NCBI): 386618
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The family of potassium channel tetramerization domain (KCTD) proteins consists of 26 members (PMID: 24268103). Potassium channel tetramerization domain containing 4 (KCTD4) is a protein that interacts with CLIC1 to disrupt calcium homeostasis and promote metastasis in esophageal cancer. KCTD4 expression is upregulated in metastatic esophageal squamous cell carcinoma (ESCC), and high KCTD4 expression is associated with poor prognosis in patients with ESCC. This process activates fibroblasts in a paracrine manner, promoting cancer cell invasion via MMP24 signaling as positive feedback (PMID: 37799381).

{{ptg:RelatedPrimaryAntibodies}}