Anticorps Polyclonal de lapin anti-KEPI

• Phare
• Validé par KD/KO

KEPI Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24933-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 24933-1-AP (same clone as 24933-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24933-1-AP (KEPI antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24933-1-PBS in a different storage buffer formulation.

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  WB analysis using 24933-1-AP (same clone as 24933-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24933-1-AP (KEPI antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24933-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 24933-1-AP (same clone as 24933-1-PBS)

  WB result of KEPI antibody (24933-1-AP; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-KEPI transfected HeLa cells. This data was developed using the same antibody clone with 24933-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24933-1-PBS cible KEPI dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KEPI Protéine recombinante Ag20645
• Nom complet: protein phosphatase 1, regulatory (inhibitor) subunit 14C
• Masse moléculaire calculée: 18 kDa
• Poids moléculaire observé: 20-22 kDa
• Numéro d’acquisition GenBank: BC015773
• Symbole du gène: PPP1R14C
• Identification du gène (NCBI): 81706
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PPP1R14C, found as a morphine‐regulated brain gene, encodes protein phosphatase 1 regulatory inhibitor subunit 14C, and is identified as a potent inhibitor of PP1. Horvath and colleagues reported that PPP1R14C inhibited the release of neurotransmitters and promoted neuronal exocytosis by retaining synaptosome associated protein 25 (SNAP25) at a phosphorylated state. Moreover, overexpression of PPP1R14C increased the phosphorylation of RB transcriptional co‐repressor 1 (RB1) to protect leukemic cells from chemotherapy.

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