- Phare
- Validé par KD/KO
Anticorps Polyclonal de lapin anti-KHSRP
KHSRP Polyclonal Antibody for WB, ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, rat, souris
Applications
WB, IF, RIP, ELISA
Conjugaison
Non conjugué
N° de cat : 55409-1-AP
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en WB | cellules HEK-293T, cellules HeLa, cellules HepG2, cellules Jurkat, cellules MCF-7, tissu cérébral de rat, tissu cérébral de souris | 
Dilution recommandée
| Application | Dilution | 
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 | 
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| KD/KO | See 2 publications below | 
| WB | See 9 publications below | 
| IF | See 2 publications below | 
| RIP | See 1 publications below | 
Informations sur le produit
55409-1-AP cible KHSRP dans les applications de WB, IF, RIP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris
| Réactivité | Humain, rat, souris | 
| Réactivité citée | Humain, souris | 
| Hôte / Isotype | Lapin / IgG | 
| Clonalité | Polyclonal | 
| Type | Anticorps | 
| Immunogène | Peptide | 
| Nom complet | KH-type splicing regulatory protein | 
| Masse moléculaire calculée | 73 kDa | 
| Poids moléculaire observé | 75 kDa | 
| Numéro d’acquisition GenBank | NM_003685 | 
| Symbole du gène | KHSRP | 
| Identification du gène (NCBI) | 8570 | 
| Conjugaison | Non conjugué | 
| Forme | Liquide | 
| Méthode de purification | Purification par affinité contre l'antigène | 
| Tampon de stockage | PBS with 0.02% sodium azide and 50% glycerol | 
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. | 
Informations générales
KHSRP, also named as FUBP2, KSRP, and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. It is involved in the degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Protocole
| Product Specific Protocols | |
|---|---|
| WB protocol for KHSRP antibody 55409-1-AP | Download protocol | 
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols | 
Publications
| Species | Application | Title | 
|---|---|---|
| Nucleic Acids Res G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities. | ||
| iScience Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1 | ||
| Atherosclerosis microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator. | ||
| Int Immunopharmacol Angiotensin II contributes to intratumoral immunosuppressionvia induction of PD-L1 expression in non-small cell lung carcinoma.
 | ||
| Cell Rep Identification of cis-HOX-HOXC10 axis as a therapeutic target for colorectal tumor-initiating cells without APC mutations.
 | ||
| Biochim Biophys Acta Subcellular quantitative proteomic analysis reveals host proteins involved in human cytomegalovirus infection. | 


