• Phare
  • Validé par KD/KO

Anticorps Polyclonal de lapin anti-KHSRP

KHSRP Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF, RIP, ELISA

Conjugaison

Non conjugué

Publications(9)

N° de cat : 55409-1-AP

Synonymes

FBP2, FUBP2, FUSE binding protein 2, KHSRP, KSRP, p75



Applications testées

Résultats positifs en WBcellules HEK-293T, cellules HeLa, cellules HepG2, cellules Jurkat, cellules MCF-7, tissu cérébral de rat, tissu cérébral de souris

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

55409-1-AP cible KHSRP dans les applications de WB, IF, RIP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Réactivité citéeHumain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Peptide
Nom complet KH-type splicing regulatory protein
Masse moléculaire calculée 73 kDa
Poids moléculaire observé 75 kDa
Numéro d’acquisition GenBankNM_003685
Symbole du gène KHSRP
Identification du gène (NCBI) 8570
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS with 0.02% sodium azide and 50% glycerol
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

KHSRP, also named as FUBP2, KSRP, and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. It is involved in the degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

Protocole

Product Specific Protocols
WB protocol for KHSRP antibody 55409-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Nucleic Acids Res

G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities.

Authors - Xiaomei He
humanWB,IF

iScience

Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1

Authors - Lingxiao Tong
humanWB

Atherosclerosis

microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator.

Authors - Huajun Jiang
humanWB

Int Immunopharmacol

Angiotensin II contributes to intratumoral immunosuppressionvia induction of PD-L1 expression in non-small cell lung carcinoma.

Authors - Kaiyong Yang
  • KD Validated
humanWB,RIP

Cell Rep

Identification of cis-HOX-HOXC10 axis as a therapeutic target for colorectal tumor-initiating cells without APC mutations.

Authors - Zhenzhen Chen
  • KO Validated
humanWB, IF

Biochim Biophys Acta

Subcellular quantitative proteomic analysis reveals host proteins involved in human cytomegalovirus infection.

Authors - Fan Chai
{{ptg:RelatedPrimaryAntibodies}}