Anticorps Monoclonal anti-KIAA0319L

KIAA0319L Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2E11D9

N° de cat : 68717-1-PBS

Synonymes

KIAA0319 like, KIAA0319L, KIAA1837, PKD1 like, PP791, RP4 765A10.3

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Galerie de données de validation

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  WB analysis using 68717-1-Ig (same clone as 68717-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68717-1-Ig (KIAA0319L antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68717-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68717-1-PBS cible KIAA0319L dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: KIAA0319L Protéine recombinante Ag15263
• Nom complet: KIAA0319-like
• Masse moléculaire calculée: 1049 aa, 116 kDa
• Poids moléculaire observé: 140-150 kDa
• Numéro d’acquisition GenBank: BC031672
• Symbole du gène: KIAA0319L
• Identification du gène (NCBI): 79932
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

KIAA0319L (also known as AAVR) is a type-I transmembrane protein that acts as a receptor for adeno-associated virus (AAV) and is involved in adeno-associated virus infection through endocytosis system (PMID: 26814968). It has been shown that KIAA0319L is highly-glycosylated and can localise to the plasma membrane, endosomes, Golgi and trans-Golgi network (TGN) (PMID: 29991750). KIAA0319L gene has been associated with susceptibility to developmental dyslexia or reading disabilities (PMID: 19085271). The predicted molecular mass of KIAA0319L is 116 kDa, but western blot detected protein at 150 kDa in lysate from HeLa cells, likely due to glycosidic linkages (PMID: 28679762; 30962536).

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