Anticorps Polyclonal de lapin anti-CEP104

CEP104 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 31847-1-AP

Synonymes

KIAA0562, Centrosomal protein of 104 kDa, Centrosomal Protein 104kDa, Centrosomal Protein 104

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Galerie de données de validation

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  WB analysis using 31847-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31847-1-AP (KIAA0562 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HeLa, cellules HepG2, cellules hTERT-RPE1, cellules K-562, cellules MOLT-4

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

31847-1-AP cible CEP104 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CEP104 Protéine recombinante Ag35662
• Nom complet: KIAA0562
• Masse moléculaire calculée: 104kDa，925aa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: NM_014704.3
• Symbole du gène: KIAA0562
• Identification du gène (NCBI): 9731
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

KIAA0562, also known as CEP104 (centrosomal protein 104), is a gene encoding a centrosomal protein that is essential for ciliogenesis and the structural integrity of the cilium tip. During ciliogenesis, CEP104 is translocated from the distal tip of the centriole to the elongated cilium tip. CEP104 is expressed in a variety of cell types, including tissues such as testis and kidney. Mutations in its gene are associated with the autosomal recessive disorder Joubert syndrome, which is characterized by distinctive mid-hindbrain and cerebellar malformations, actinic dyskinesia, irregular breathing, developmental delay, and ataxia. In studies, inhibitors of CEP104 such as Cytochalasin D and Vismodegib have been used to investigate their specific role in cellular function.

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