Anticorps Polyclonal de lapin anti-KIAA1217

KIAA1217 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24880-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 24880-1-AP (same clone as 24880-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24880-1-AP (KIAA1217 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24880-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse colon using 24880-1-AP (same clone as 24880-1-PBS)

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 24880-1-AP (KIAA1217 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24880-1-PBS in a different storage buffer formulation.

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  WB analysis using 24880-1-AP (same clone as 24880-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 24880-1-AP (KIAA1217 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24880-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 24880-1-AP (same clone as 24880-1-PBS)

  Rat colon lysates were subjected to SDS PAGE followed by western blot with 24880-1-AP (KIAA1217 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24880-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24880-1-PBS cible KIAA1217 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KIAA1217 Protéine recombinante Ag19367
• Nom complet: KIAA1217
• Masse moléculaire calculée: 1943 aa, 214 kDa
• Poids moléculaire observé: 100-110 kDa, 140-160 kDa, 210 kDa
• Numéro d’acquisition GenBank: BC018764
• Symbole du gène: KIAA1217
• Identification du gène (NCBI): 56243
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

KIAA1217, sickle tail protein homolog, is required for normal development of intervertebral disks. It promotes epithelial-mesenchymal transition and hepatocellular carcinoma metastasis by interacting with and activating STAT3, indicating its potential as a therapeutic target for curbing HCC metastasis (PMID: 35008530). It is also a novel candidate gene associated with isolated and syndromic vertebral malformations (PMID: 32369272). KIAA1217 has 9 alternatively spliced isoforms of 100-110 kDa, 140-160 kDa, 210 kDa.

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