Anticorps Polyclonal de lapin anti-RIC1

RIC1 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32377-1-PBS

Synonymes

CIP150, KIAA1432, Protein RIC1 homolog, Q4ADV7

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Galerie de données de validation

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  WB analysis using 32377-1-AP (same clone as 32377-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32377-1-AP (KIAA1432 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32377-1-PBS in a different storage buffer formulation.

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  IP experiment of HeLa using 32377-1-AP (same clone as 32377-1-PBS)

  IP result of anti-RIC1 (IP:32377-1-AP, 4ug; Detection:32377-1-AP 1:1000) with HeLa cells lysate 1880 ug. This data was developed using the same antibody clone with 32377-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32377-1-PBS cible RIC1 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RIC1 Protéine recombinante Ag36426
• Nom complet: KIAA1432
• Poids moléculaire observé: 150 kDa
• Numéro d’acquisition GenBank: BC136616
• Symbole du gène: KIAA1432
• Identification du gène (NCBI): 57589
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RIC1 (RAB6A GEF complex partner 1) is a protein that plays a critical role in intracellular membrane trafficking. It encodes a protein of 1056 amino acid (aa) residues, including a putative nuclear localisation sequence (PMID: 9099877). Ric1 is composed of two β-propellers and a C-terminal α-solenoid domain that remodels the Rab6 nucleotide-binding pocket to facilitate nucleotide exchange (PMID: 39632878). RIC1 proteins play important roles in vesicular trafficking, regulation of membrane dynamics, cell division and signalling, and are essential for maintaining normal cellular function.

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