Anticorps Monoclonal anti-KIAA2013

KIAA2013 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, rat

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

4G6C4

N° de cat : 68245-1-PBS

Synonymes

4G6C4

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Galerie de données de validation

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  WB analysis using 68245-1-Ig (same clone as 68245-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68245-1-Ig (KIAA2013 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68245-1-PBS in a different storage buffer formulation.

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  WB analysis using 68245-1-Ig (same clone as 68245-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68245-1-Ig (KIAA2013 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68245-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 68245-1-Ig (same clone as 68245-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using KIAA2013 antibody (68245-1-Ig, Clone: 4G6C4 ) at dilution of 1:1000 and Multi-rAb CoraLite® Plus 594-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (Cat.NO. RGAM004 ). This data was developed using the same antibody clone with 68245-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68245-1-PBS cible KIAA2013 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: KIAA2013 Protéine recombinante Ag27438
• Nom complet: KIAA2013
• Poids moléculaire observé: 65 kDa
• Numéro d’acquisition GenBank: BC035033
• Symbole du gène: KIAA2013
• Identification du gène (NCBI): 90231
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

KIAA2013, also known as Q8IYS2 or MGC33867, is a single-pass transmembrane protein encoded by the KIAA2013 gene in humans. KIAA2013 has been found to play a role in the Endocannabinoid system. This system is made up of cannabinoid receptors 1 and 2 (CB1 and CB2) as well as the various ligands and enzymes that interact. The protein KIAA2013 has been found to be expressed within CB2 expressing cells. Both cannabinoid receptors are labeled as class A G-Protein Coupled Receptors, and CB2 is highly expressed within the human spleen and leukocytes. CB2, and by extension KIAA2013, are therefore targets of interest for therapeutic studies looking into diseases such as inflammatory bowel disease and rheumatoid arthritis(PMID:31616248 34752341).

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