Anticorps Monoclonal anti-KIDINS220

KIDINS220 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3G2D8

N° de cat : 66748-1-PBS

Synonymes

ARMS, KIAA1250, KIDINS220

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Galerie de données de validation

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  WB analysis using 66748-1-Ig (same clone as 66748-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66748-1-Ig (KIDINS220 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66748-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66748-1-PBS cible KIDINS220 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: KIDINS220 Protéine recombinante Ag17624
• Nom complet: kinase D-interacting substrate, 220kDa
• Masse moléculaire calculée: 1672 aa, 187 kDa
• Poids moléculaire observé: 200 kDa
• Numéro d’acquisition GenBank: BC130610
• Symbole du gène: KIDINS220
• Identification du gène (NCBI): 57498
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Kidins220 (Kinase D-interacting substrate 220 kD) is a crucial mediator of signal transduction in neural tissues. Also it named ARMS(Ankyrin Repeat-Rich Membrane Spanning) due to the presence of ankyrin repeats and transmembrane domains together with other binding motifs. It is a multidomain transmembrane protein that not only transduces signaling mediated by the receptor tyrosine kinase (RTK), but also regulates the stability of cytoskeletal network through a number of cytoskeleton-associated proteins, including Septin5, MAPs , and stathmin family members. KIDINS220 exists some isoforms with MV 194 kDa, 185 kDa, 115 kDa, and 60 kDa.

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