Anticorps Recombinant de lapin anti-KIF2A

KIF2A Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

250946C7

N° de cat : 86268-3-RR

Synonymes

HK2, KIF2, Kinesin 2, kinesin heavy chain member 2A, Kinesin like protein KIF2A

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Galerie de données de validation

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  WB analysis using 86268-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 86268-3-RR (KIF2A antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

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  WB analysis using 86268-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 86268-3-RR (KIF2A antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 86268-3-RR

  Biolayer interferometry (BLl) kinetic assays of 86268-3-RR against Human KIF2A were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en WB: cellules HeLa, cellules A549, cellules Jurkat, cellules NCI-H1299, tissu cérébral de rat, tissu cérébral de souris

Dilution recommandée

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

86268-3-RR cible KIF2A dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: KIF2A Protéine recombinante Ag3748
• Nom complet: kinesin heavy chain member 2A
• Masse moléculaire calculée: 679 aa, 77 kDa
• Poids moléculaire observé: 80-100 kDa
• Numéro d’acquisition GenBank: BC031828
• Symbole du gène: KIF2A
• Identification du gène (NCBI): 3796
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Kinesin family member 2a (KIF2A), one of the kinesin family members, is identified in mammalian cells and involved in regulating microtubule dynamics during the mitosis via modulating intracellular transport, cell division, and bipolar spindle assembly (PMID: 17538014). High expression of KIF2A correlates with advanced tumor stages and worse prognosis in non-small cell lung cancer patients (PMID: 31858647). Within clinical practice, KIF2A exhibits key prognostic value for the management of gastric cancer, colorectal cancer and nasopharyngeal carcinoma (PMID: 32106376, PMID: 26070867, PMID: 26602436).

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