Anticorps Monoclonal anti-KIF5A

KIF5A Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1A7E3

N° de cat : 67009-1-PBS

Synonymes

D12S1889, KIF5A, kinesin family member 5A, Kinesin heavy chain isoform 5A, MY050, Neuronal kinesin heavy chain, NKHC, NKHC1, SPG10

---

Galerie de données de validation

• 

  WB analysis using 67009-1-Ig (same clone as 67009-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67009-1-Ig (KIF5A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67009-1-PBS in a different storage buffer formulation.

• 

  WB analysis of pig brain using 67009-1-Ig (same clone as 67009-1-PBS)

  pig brain tissue were subjected to SDS PAGE followed by western blot with 67009-1-Ig (KIF5A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67009-1-PBS in a different storage buffer formulation.

• 

  IF Staining of PC-12 using 67009-1-Ig (same clone as 67009-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed PC-12 cells using KIF5A antibody (67009-1-Ig, Clone: 1A7E3 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67009-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

67009-1-PBS cible KIF5A dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: KIF5A Protéine recombinante Ag15682
• Nom complet: kinesin family member 5A
• Masse moléculaire calculée: 1032 aa, 117 kDa
• Poids moléculaire observé: 130 kDa
• Numéro d’acquisition GenBank: BC146670
• Symbole du gène: KIF5A
• Identification du gène (NCBI): 3798
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Kinesin superfamily proteins (KIFs) are microtubule-based molecular motors essential for the intracellular transport of various cargos, including organelles, proteins, and RNAs. KIF5A is expressed exclusively in neurons and transports neuronal cargoes into axons and dendrites. KIF5A mutations have been associated with Charcot-Marie-Tooth Type 2, an axonal peripheral neuropathy characterized by progressive loss of peripheral sensation and muscle wasting.

{{ptg:RelatedPrimaryAntibodies}}