Anticorps Polyclonal de lapin anti-KIF7

• Phare
• Validé par KD/KO

KIF7 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24693-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of HEK-293 using 24693-1-AP (same clone as 24693-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 24693-1-AP (KIF7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24693-1-PBS in a different storage buffer formulation.

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  WB analysis using 24693-1-AP (same clone as 24693-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24693-1-AP (KIF7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24693-1-PBS in a different storage buffer formulation.

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  IP experiment of HEK-293 using 24693-1-AP (same clone as 24693-1-PBS)

  IP result of anti-KIF7 (IP:24693-1-AP, 5ug; Detection:24693-1-AP 1:500) with HEK-293 cells lysate 1760ug. This data was developed using the same antibody clone with 24693-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24693-1-PBS cible KIF7 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KIF7 Protéine recombinante Ag19119
• Nom complet: kinesin family member 7
• Masse moléculaire calculée: 1343 aa, 151 kDa
• Poids moléculaire observé: 140 kDa
• Numéro d’acquisition GenBank: BC112271
• Symbole du gène: KIF7
• Identification du gène (NCBI): 374654
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

KIF7(Kinesin family member 7) is a microtubule interacting protein that functions to regulate Hh signaling by maintaining the architecture of the primary cilium, a complex microtubule-based organelle with many signal transduction functions (PMID: 26439735). KIF7 has been shown to have both negative and positive roles in Shh signal transduction. Without a ligand, KIF7 localizes to the cilium base where it forms a complex with Gli proteins and other pathway components and promotes the processing of GliRs (PMID: 21552264).

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