Anticorps Polyclonal de lapin anti-KIR3DL1/CD158E

KIR3DL1/CD158E Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13335-1-PBS

Synonymes

KIR3DL1, CD158 antigen-like family member E, CD158E, CD158E1, HLA-BW4-specific inhibitory NK cell receptor

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Galerie de données de validation

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  WB analysis using 13335-1-AP (same clone as 13335-1-PBS)

  human peripheral blood leukocytes were subjected to SDS PAGE followed by western blot with 13335-1-AP (KIR3DL1/CD158E antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13335-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13335-1-PBS cible KIR3DL1/CD158E dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KIR3DL1/CD158E Protéine recombinante Ag4152
• Nom complet: killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
• Masse moléculaire calculée: 444 aa, 49 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC028206
• Symbole du gène: KIR3DL1
• Identification du gène (NCBI): 3811
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous. This antibody is raised against 22-344 amino acids of human KIR3DL1 and recognizes both KIR3DL1 (49 kDa) and KIR3DS1 (43 kDa).

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